Design and Synthesis of BODIPY‐Hetero[5]helicenes as Heavy‐Atom‐Free Triplet Photosensitizers for Photodynamic Therapy of Cancer

With light excitation, triplet oxygen molecules (3O2; red dots) are converted to singlet (1O2; blue through photosensitization by the BODIPY-hetero[5]helicene (BHH) molecule. The researcher is trying increase twist angle of BHH. As it increases, stick indicating percentage 1O2 conversion moves towards 100. This illustrates how increases with increasing BHH angle, which main highlight work. More information can be found in Research Article S. Mula and co-workers (DOI: 10.1002/chem.202301605).